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Cannabis Destroys Sleep Quality
A 35-year study shows cannabis use links to fragmented, poor sleep measured by monitors, even though users believe they slept well.
Genetic Risk for Anorexia May Begin Outside the Brain
Anorexia patients are 4x more likely to carry mutations in PLIN4, a fat-storage gene in muscle and adipose tissue, revealing a key metabolic component.
Higher BMI Linked to Longer Survival After a Dementia Diagnosis
A study of 4,500+ adults shows overweight or obese BMI at dementia diagnosis is linked to significantly lower mortality risk, highlighting metabolic reserves.
Can We Predict Hearing Loss Long Before Symptoms Ever Start?
Precision phenotyping combining audiometric data and genetics predicts sensorineural hearing loss far more accurately than standard billing codes.
How Dark Traits Reshape Speech
A new study reveals psychopathic traits like boldness, meanness, and disinhibition drive distinct, complex language patterns.
How Brain Cells Lock In Short-Term Memories
A new study reveals a "split attractor network" in fruit flies that explains how neural circuits stabilize short-term working memories.
Microglia Rescue Vulnerable Dopamine Neurons in Parkinson’s
Summary: Researchers at the University of Oxford have discovered that human microglia can selectively prune away toxic alpha-synuclein aggregates from dopamine-producing neurons without destroying the host nerve cells. Utilizing co-cultures of human induced pluripotent stem cell (iPSC)-derived neurons and microglia, the team demonstrated that microglia employ “trogocytosis”, a precise cellular nibbling mechanism, regulated by GPNMB, P2RY12, and CD22 signaling pathways, along with an IL-10 molecular brake.
Statins Linked to Reduced Glaucoma Risk and Slower Progression
A new study in 420,000 adults links statin medications to a 15% lower glaucoma risk and a 55% drop in surgical interventions.
A Single Neural Circuit Unifies Multidimensional Prediction
Researchers show a single spiking neural network predicts event identity, timing, and probability using local learning.
Adults With ADHD Face Higher Long-Term Dementia Risk
Adults with ADHD have over 4 times the risk of dementia, backed by genetic data from 187,000 older adults.
AI Chatbots Are Hardwired to Defend the Status Quo
A new study of 11 AI models reveals chatbots systematically favor the status quo, advising against electric vehicles and climate policies.
Early DBS Protects Cognition in Genetic Parkinson’s
Timing of DBS surgery is critical to preserve cognitive function in Parkinson's patients with GBA1 mutations.
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